Kaylee: [about Simon] You shouldn't be so rude to him. Jayne: Why? Cause he's all rich and fanciable?
— Tim Minear, Joss Whedon, Kaylee Frye, Jewel Staite, imdb.com
Episode
The crew of Serenity take on a train heist commissioned by a crime lord. They steal the goods, only to find it is medicine that's desperately needed by the town.
Kaylee: [about Simon] You shouldn't be so rude to him. Jayne: Why? Cause he's all rich and fanciable?
— Tim Minear, Joss Whedon, Kaylee Frye, Jewel Staite, imdb.com
We didn't fly 86 million miles to track down a box of Band-Aids, Colonel.
— Tim Minear, Joss Whedon, Hands of Blue, Dennis Cockrum, imdb.com
Book: How's the girl? Mal: Still a little whimsical in the brainpan. Seems calm enough, though. Mal: [River knocks over a tray of medical instruments; both look her way at the sound of instruments clattering] Mm-hmm. Book: That young man's very brave. Mal: Yeah. [sarcastically] Mal: He's my hero. Bo…
— Tim Minear, Joss Whedon, Malcolm Reynolds, Nathan Fillion, imdb.com
[after Inara has been doing Kaylee's hair and Mal has ordered her out] Mal: You're servicing crew now. Inara Serra: [snickers] In your lonely, pathetic dreams.
— Tim Minear, Joss Whedon, Inara Serra, Morena Baccarin, imdb.com
That sounds like the Alliance. Unite all the planets under one rule so that everybody can be interfered with or ignored equally.
— Tim Minear, Joss Whedon, Malcolm Reynolds, Nathan Fillion, imdb.com
Zoë: Jayne? Jayne: Hey, I didn't fight in no war. Best o' luck, though.
— Tim Minear, Joss Whedon, Jayne Cobb, Adam Baldwin, imdb.com
These are stone killers, little man. They ain't cuddly like me.
— Tim Minear, Joss Whedon, Jayne Cobb, Adam Baldwin, imdb.com
Ladies and menfolk…[holds out a slip of paper]…we have ourselves a job. Take us out of the world, Wash. Got us some crime to be done.
— Tim Minear, Joss Whedon, Malcolm Reynolds, Nathan Fillion, imdb.com
Mal: [after getting tossed out a simulated bar window] Wash, we got some local color happening. A grand entrance would not go amiss. [Zoe comes out fighting a drunk; more join in as Mal takes on the one Zoe knocked down] Mal: Is Jayne even awake? [Jayne comes out fighting two at once, pushing them b…
— Tim Minear, Joss Whedon, Malcolm Reynolds, Nathan Fillion, imdb.com
You're a very 'up' person.
— Tim Minear, Joss Whedon, Zoë Washburne, Gina Torres, imdb.com
Mal: [backed up against the edge of a cliff, facing the drunks from the bar] Oh, ho-ho! There's just an acre of you fellas, isn't there? This is why we lost, you know. Superior numbers. Zoë: Thanks for the reenactment, sir.
— Tim Minear, Joss Whedon, Zoë Washburne, Gina Torres, imdb.com
Book: So...how do you think it's going? Inara: The caper? Mal knows what he's doing. Book: How long have you known him? Inara: I've been on the ship eight months now. I'm not certain I'll ever actually know the captain.
— Tim Minear, Joss Whedon, Inara Serra, Morena Baccarin, imdb.com
Sheriff Bourne: We had some, uh, unrelated trouble. His story had kind of an odor to it. Inara Serra: Yes, it's not the only thing about him that does.
— Tim Minear, Joss Whedon, Inara Serra, Morena Baccarin, imdb.com
Niska: Oh, you do not like I kill this man? Mal: Oh no, I'm sure he was a...very bad person.
— Tim Minear, Joss Whedon, Malcolm Reynolds, Nathan Fillion, imdb.com
Mal: [on Niska] He's not the first psycho to hire us. Nor the last. You think that's a commentary on us? Zoë: I just have an image in my head of a guy hanging from the ceiling. Mal: I've got an image of it not being me. Let's do the thing.
— Tim Minear, Joss Whedon, Malcolm Reynolds, Nathan Fillion, imdb.com
Sheriff Bourne: You mind telling me, uh, when it was you last spoke to Joey Bloggs? Mal: Never did, myself. Sheriff Bourne: Right. Your uncle. And it was indicated to you that, uh, Joey had an opening? Mal: Any job would do. Sheriff Bourne: It's funny your Uncle never went to mentioning the Bowden's…
— Tim Minear, Joss Whedon, Malcolm Reynolds, Nathan Fillion, imdb.com
Inara: You have such lovely hair. I'm sure the doctor would agree. Kaylee: Who? Simon? No, he's much too—I mean I'm just—do you think it looks better up? Inara: We can experiment. We might even get wild later and wash your face.
— Tim Minear, Joss Whedon, Inara Serra, Morena Baccarin, imdb.com
Jayne: [the three of them are playing Chinese checkers; to Mal] Your move. [Mal jumps four marbles] Zoë: That's a bold move. Mal: I live on the edge. [Zoe jumps six of his marbles] Jayne: Nice work, dumbass. Mal: [as Zoe chuckles] I've given some thought to moving off the edge. Not an ideal location…
— Tim Minear, Joss Whedon, Jayne Cobb, Adam Baldwin, imdb.com
[Jayne takes out Crow with leg shot] Mal: Nice shot! Jayne: [sitting on the floor, drugged] I was aiming for his head.
— Tim Minear, Joss Whedon, Jayne Cobb, Adam Baldwin, imdb.com
Book: I wish I could help. [Inara turns to face him & he realizes what he said] I mean...I don't wanna help—not help help, but—not with the thieving, but— [Inara smiles, tries not to laugh] Book: I do feel awfully useless. Inara: You could always pray they make it back safely. Book: I don't think th…
— Tim Minear, Joss Whedon, Inara Serra, Morena Baccarin, imdb.com